How do you treat someone who really gets under your skin, or someone who's not part of the crowd, or who seems a bit weird, or different? You can treat them in whichever way you choose, but it pays off to be tolerent, to befriend, to go along with the joke, to be accepting. You never know, an act of kindness in the present could turn out to be worth much more in the future.
Hold a higher standard of character.
Be the one who makes the effort.